Open AccessA novel hepatitis B virus mutant with A-to-G at nt551 in the surface antigen gene
Author(s) -
Hua-Biao Chen,
Dexing Fang,
Faqing Li,
Hui-Ying Jing,
Weiguo Tan,
Suqin Li
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i2.304
Subject(s) - hbsag , hepatitis b virus , virology , biology , mutant , hepatitis b virus pre beta , microbiology and biotechnology , hepadnaviridae , antibody , hepatitis b virus dna polymerase , virus , gene , immunology , genetics
Hepatitis B surface antigen (HBsAg) mutant of hepatitis B virus (HBV) is one of the important factors that result in immune escape and cause failure of immunization. In this study we reported and characterized a novel HBV mutant with A-to-G at nt551 and intended to provide theoretical data for prevention of HBV infection in China.