Open AccessTargeted ribonuclease can inhibit replication of hepatitis B virus
Author(s) -
Jun Li,
Yinghui Li,
Cong Xue,
Jin Ding,
Weidong Gong,
Ya Zhao,
Yongye Huang
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i2.295
Subject(s) - transfection , microbiology and biotechnology , biology , ribonuclease , cytotoxicity , cytotoxic t cell , hepatitis b virus , virology , hbsag , transgene , in vitro , cell culture , virus , gene , rna , biochemistry , genetics
To study the effect of a novel targeted ribonuclease (TN), the fusion protein of HBVc and human eosinophil-derived neurotoxin (hEDN), on the HBV replication in vitro.