Impact of endoscopically minimal involvement on IL-8 mRNA expression in esophageal mucosa of patients with non-erosive reflux disease | Zendy

Yusei Kanazawa | Zendy

Open Access

Impact of endoscopically minimal involvement on IL-8 mRNA expression in esophageal mucosa of patients with non-erosive reflux disease

Author(s) -

Yusei Kanazawa

Publication year - 2003

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v9.i12.2801

Subject(s) - nerd , esophagus , reflux , gastroenterology , medicine , pathogenesis , gerd , asymptomatic , esophageal disease , pathology , biopsy , real time polymerase chain reaction , esophagitis , reverse transcription polymerase chain reaction , messenger rna , disease , biology , gene , biochemistry

Little has been known about the pathogenesis of non-erosive reflux disease (NERD). Recent studies have implicated interleukin 8 (IL-8) in the development and progression of gastroesophogeal reflux disease (GERD). The purpose of this study was to determine IL-8 RNA expression levels in NERD patients with or without subtle mucosal changes.

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