Open AccessVisceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis
Author(s) -
Jun–Ho La,
Tae Wan Kim,
Tae Sik Sung,
Jeoung Woo Kang,
Hyun Ju Kim,
Inho Yang
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i12.2791
Subject(s) - colitis , irritable bowel syndrome , medicine , inflammatory bowel disease , inflammation , gastroenterology , motility , visceral pain , myeloperoxidase , distension , defecation , pathogenesis , rectum , pathology , nociception , disease , biology , receptor , genetics
Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by visceral hypersensitivity and altered bowel motility. There is increasing evidence suggesting the role of inflammation in the pathogenesis of IBS, which addresses the possibility that formerly established rat model of colitis could be used as an IBS model after the inflammation subsided.