Open AccessAntiproliferative effect of octreotide on gastric cancer cells mediated by inhibition of Akt/PKB and telomerase
Author(s) -
Shan Gao,
Baoping Yu,
Yan Li,
Weiguo Dong,
Hao Luo
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i10.2362
Subject(s) - octreotide , protein kinase b , telomerase , somatostatin , cell culture , mtt assay , chemistry , cancer cell , cell growth , cancer , cancer research , medicine , endocrinology , microbiology and biotechnology , pharmacology , biology , signal transduction , biochemistry , genetics , gene
To investigate the antiproliferative effect of octreotide, a long-acting analogue of somatostatin, on gastric cancer cell line SGC7901 and its possible molecular mechanisms.