Open AccessPathophysiological aspects of diverticular disease of colon and role of large bowel motility
Author(s) -
Gabrio Bassotti,
Fabio Chistolini,
Antonio Morelli
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i10.2140
Subject(s) - diverticular disease , diverticulosis , pathophysiology , medicine , disease , motility , etiology , pathogenesis , gastroenterology , gastrointestinal disease , bioinformatics , biology , genetics
Colonic diverticular disease (diverticulosis) is one of the most common gastrointestinal disorders in Western countries. This disorder is strictly related to aging and fibre intake, and still bears a discrete amount of morbidity. Numerous etiological co-factors have to date been implicated in the pathogenesis of the disease, yet the supporting evidence is still far from absolute. The present review considers the pathophysiology of colonic diverticular disease, with a special emphasis on factors related to abnormal colonic motility.