Open AccessSilencing-specific methylation and single nucleotide polymorphism ofhMLH1promoter in gastric carcinomas
Author(s) -
Dajun Deng,
Jin Zhang,
Budong Zhu,
Jiafu Ji,
Jeffrey C. Harper,
Steven M. Powell
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i1.26
Subject(s) - methylation , microbiology and biotechnology , dna methylation , biology , single nucleotide polymorphism , bisulfite sequencing , cpg site , epigenetics , denaturing high performance liquid chromatography , carcinoma , gene silencing , snp , cancer research , gene , polymerase chain reaction , genetics , gene expression , genotype
To investigate CpG methylation and single nucleotide polymorphism (SNP) of a specific promoter region of hMLH1 in primary gastric carcinoma.