Open AccessProgressive transformation of immortalized esophageal epithelial cells
Author(s) -
Zhong-Ying Shen,
Li Xu,
Minhua Chen,
Jian Shen,
Weijia Cai,
Yi Zeng
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i6.976
Subject(s) - telomerase , biology , karyotype , cell culture , flow cytometry , contact inhibition , transfection , cell growth , epithelium , microbiology and biotechnology , malignant transformation , cell , cell division , pathology , chromosome , cancer research , genetics , gene , medicine
To investigate the progressive transformation of immortal cells of human fetal esophageal epithelium induced by human papillomavirus, and to examine biological criteria of sequential passage of cells, including cellular phenotype, proliferative rate, telomerase, chromosome and tumorigenicity.