Open AccessExpression of exogenous rat collagenasein vitroand in a rat model of liver fibrosis
Author(s) -
Jiyao Wang,
Jinsheng Guo,
Changqing Yang
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i5.901
Subject(s) - collagenase , in vivo , microbiology and biotechnology , transfection , hepatic stellate cell , biology , cell culture , in vitro , blot , gene expression , interstitial collagenase , chemistry , biochemistry , enzyme , endocrinology , gene , genetics
The present study was conducted to test the hypothesis that the introduction of the collagenase gene into tissue culture cells and into a rat model of liver fibrosis would result in the expression of enzymatically active product.