Open AccessEffects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15
Author(s) -
Jie Li,
Wei Guo,
Yang Qingyao
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i3.493
Subject(s) - flow cytometry , cytotoxicity , oleanolic acid , cell culture , ursolic acid , cell growth , cell cycle , microbiology and biotechnology , cell , cell counting , chemistry , biology , biochemistry , in vitro , medicine , pathology , chromatography , genetics , alternative medicine
Ursolic acid (UA) and oleanolic acid (OA) are triperpene acids having a similar chemical structure and are distributed wildly in plants all over the world. In recent years, it was found that they had marked anti-tumor effects. There is little literature currently available regarding their effects on colon carcinoma cells. The present study was designed to investigate their inhibitory effects on human colon carcinoma cell line HCT15.