Open AccessConstruction and characterization of an experimental ISCOMS-based hepatitis B polypeptide vaccine
Author(s) -
Xiao-Ju Guan,
Xiaojun Guan,
Yuzhang Wu,
Zhengcai Jia,
Tao Shi,
Tao Yan
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i2.294
Subject(s) - elispot , immunogenicity , microbiology and biotechnology , epitope , hbsag , ctl* , virology , chemistry , immune system , biology , hepatitis b virus , t cell , antigen , immunology , cd8 , virus
To characterize the biochemical and immunological properties of an experimental ISCOMS vaccine prepared from a novel therapeutic polypeptide based on T cell epitopes of HBsAg, and a heptatis B-ISCOMS was prepared and investigated.