Open AccessJTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential
Author(s) -
Hongliang Li,
Dandan Chen,
Xiaohong Li,
Haiwei Zhang,
Jun-Hua Lü,
Xian-Da Ren,
Cunchuan Wang
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i2.217
Subject(s) - cytochrome c , apoptosis , caspase , mitochondrial apoptosis induced channel , microbiology and biotechnology , biology , intrinsic apoptosis , caspase 3 , caspase 9 , programmed cell death , tunel assay , mitochondrion , bcl 2 associated x protein , apoptosome , caspase 2 , biochemistry
To investigate the role of the mitochondrial pathway in JTE-522-induced apoptosis and to investigate the relationship between cytochrome C release, caspase activity and loss of mitochondrial membrane potential (Deltapsim).