JTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential | Zendy

Hongliang Li | Zendy; Dandan Chen | Zendy; Xiaohong Li | Zendy; Haiwei Zhang | Zendy; Jun-Hua Lü | Zendy; Xian-Da Ren | Zendy; Cunchuan Wang | Zendy

Open Access

JTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential

Author(s) -

Hongliang Li,

Dandan Chen,

Xiaohong Li,

Haiwei Zhang,

Jun-Hua Lü,

Xian-Da Ren,

Cunchuan Wang

Publication year - 2002

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v8.i2.217

Subject(s) - cytochrome c , apoptosis , caspase , mitochondrial apoptosis induced channel , microbiology and biotechnology , biology , intrinsic apoptosis , caspase 3 , caspase 9 , programmed cell death , tunel assay , mitochondrion , bcl 2 associated x protein , apoptosome , caspase 2 , biochemistry

To investigate the role of the mitochondrial pathway in JTE-522-induced apoptosis and to investigate the relationship between cytochrome C release, caspase activity and loss of mitochondrial membrane potential (Deltapsim).

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