Open AccessChiral metabolism of propafenone in rat hepatic microsomes treated with two inducers
Author(s) -
Quan Zhou,
Tong-wei Yao,
Su Zeng
Publication year - 2001
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v7.i6.830
Subject(s) - propafenone , stereoselectivity , microsome , metabolite , metabolism , chemistry , enantiomer , substrate (aquarium) , enzyme , stereochemistry , pharmacology , biochemistry , medicine , biology , ecology , atrial fibrillation , catalysis
To study the influence of inducers of drug metabolism enzyme, beta-naphthoflavone (BNF) and dexamethasone (DEX), on the stereoselective metabolism of propafenone in the rat hepatic microsomes.