Open AccessAPC and K-ras gene mutation in aberrant crypt foci of human colon
Author(s) -
Peng Yuan,
Menghong Sun,
Jinsheng Zhang,
Xiong-Zeng Zhu,
Daren Shi
Publication year - 2001
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v7.i3.352
Subject(s) - mutation , adenoma , gene mutation , aberrant crypt foci , microdissection , gene , biology , gene cluster , microbiology and biotechnology , colorectal cancer , cancer research , pathology , cancer , genetics , medicine , colonic disease
To study the genetic alteration in ACF and to define the possibility that ACF may be a very early morphological lesion with molecular changes,and to explore the relationship between ACF and colorectal adenoma even carcinoma.