Open AccessTransplantation of human hepatocytes into tolerized genetically immunocompetent rats
Author(s) -
Edwin C. Ouyang,
Catherine H. Wu,
Cherie M. Walton,
Kittichai Promrat,
George Y. Wu
Publication year - 2001
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v7.i3.324
Subject(s) - transplantation , spleen , biology , hepatocyte , immunosuppression , andrology , immunohistochemistry , albumin , chimera (genetics) , immunology , microbiology and biotechnology , medicine , endocrinology , gene , in vitro , biochemistry
To determine whether normal genetically immunocompetent rodent hosts could be manipulated to accept human hepatocyte transplants with long term survival without immunosuppression.