
Mucin and phospholipids determine viscosity of gallbladder bile in patients with gallstones
Author(s) -
Dieter Jüngst,
Aniemeyer,
I. Müller,
Benedikta Zündt,
G. Meyer,
Martin Wilhelmi,
Reginald Del Pozo
Publication year - 2001
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v7.i2.203
Subject(s) - mucin , gallstones , gallbladder , medicine , gastroenterology , cholesterol , chemistry , viscosity , biochemistry , materials science , composite material
An increased viscosity of gallbladder bile has been considered an important factor in the pathogenesis of gallstone disease. Besides lipids and proteins, mucin has been suggested to affect the viscosity of bile. To further clarify these issues we compared mucin, protein and the lipid componEnts of hepatic and gallbladder bile and its viscosity in patients with gallstones.