Open AccessPeroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication for esophageal achalasia: A single-center randomized controlled trial
Author(s) -
Eduardo Turiani Hourneaux de Moura,
José Jukemura,
Igor Braga Ribeiro,
Galileu F. Farias,
Áureo Delgado,
Lara Coutinho,
Diogo Turiani Hourneaux de Moura,
Rubens Antônio Aissar Sallum,
Ary Nasi,
Sergio A. Sánchez-Luna,
Paulo Sakai,
Eduardo Guimarães Hourneaux de Moura
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i33.4875
Subject(s) - achalasia , myotomy , medicine , dysphagia , heller myotomy , reflux esophagitis , reflux , surgery , esophagitis , randomized controlled trial , esophagus , esophageal motility disorder , adverse effect , esophageal sphincter , gastroenterology , disease
Achalasia is a rare benign esophageal motor disorder characterized by incomplete relaxation of the lower esophageal sphincter (LES). The treatment of achalasia is not curative, but rather is aimed at reducing LES pressure. In patients who have failed noninvasive therapy, surgery should be considered. Myotomy with partial fundoplication has been considered the first-line treatment for non-advanced achalasia. Recently, peroral endoscopic myotomy (POEM), a technique that employs the principles of submucosal endoscopy to perform the equivalent of a surgical myotomy, has emerged as a promising minimally invasive technique for the management of this condition.