Open AccessThe mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway
Author(s) -
Junjian Liu,
Yan Xu,
Shuai Chen,
Cui Hao,
Jing Liang,
ZhongLian Li
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i32.4635
Subject(s) - bile duct , medicine , decoction , liver injury , jaundice , traditional chinese medicine , gastroenterology , kegg , laparotomy , common bile duct , liver function , gene ontology , pharmacology , surgery , pathology , biology , gene , gene expression , biochemistry , alternative medicine
Obstructive jaundice (OJ) is caused by bile excretion disorder after partial or complete bile duct obstruction. It may cause liver injury through various mechanisms. Traditional Chinese medicine (TCM) has a lot of advantages in treating OJ. The recovery of liver function can be accelerated by combining Chinese medicine treatment with existing clinical practice. Yinchenhao decoction (YCHD), a TCM formula, has been used to treat jaundice. Although much progress has been made in recent years in understanding the mechanism of YCHD in treating OJ-induced liver injury, it is still not clear.