Open AccessApplication of computed tomography-based radiomics in differential diagnosis of adenocarcinoma and squamous cell carcinoma at the esophagogastric junction
Author(s) -
Ke-Pu Du,
Wenpeng Huang,
Si-Yun Liu,
Yunjin Chen,
Liming Li,
XiaoNan Liu,
Yijing Han,
Yue Zhou,
Chenchen Liu,
Jianbo Gao
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i31.4363
Subject(s) - medicine , receiver operating characteristic , radiology , adenocarcinoma , univariate analysis , logistic regression , lymph node , carcinoma , stage (stratigraphy) , neoadjuvant therapy , cancer , multivariate analysis , breast cancer , paleontology , biology
The biological behavior of carcinoma of the esophagogastric junction (CEGJ) is different from that of gastric or esophageal cancer. Differentiating squamous cell carcinoma of the esophagogastric junction (SCCEG) from adenocarcinoma of the esophagogastric junction (AEG) can indicate Siewert stage and whether the surgical route for patients with CEGJ is transthoracic or transabdominal, as well as aid in determining the extent of lymph node dissection. With the development of neoadjuvant therapy, preoperative determination of pathological type can help in the selection of neoadjuvant radiotherapy and chemotherapy regimens.