Open AccessSalivary Fusobacterium nucleatum serves as a potential diagnostic biomarker for gastric cancer
Author(s) -
WenDan Chen,
Xin Zhang,
Meng-Jiao Zhang,
Yaping Zhang,
Ziqi Shang,
Yiwei Xin,
Yi Zhang
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i30.4120
Subject(s) - saliva , fusobacterium nucleatum , carcinoembryonic antigen , medicine , biomarker , gastroenterology , cancer , receiver operating characteristic , western blot , polymerase chain reaction , pancreatic cancer , pathology , biology , periodontitis , porphyromonas gingivalis , biochemistry , gene
As one of the most common tumors, gastric cancer (GC) has a high mortality rate, since current examination approaches cannot achieve early diagnosis. Fusobacterium nucleatum (Fn) primarily colonized in the oral cavity, has been reported to be involved in the development of gastrointestinal tumor. Until now, little is known about the relationship between salivary Fn and GC.