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The high prevalence and persistence of Helicobacter pylori ( H. pylori ) infection, as well as the diversity of pathologies related to it, suggest that the virulence factors used by this microorganism are varied. Moreover, as its proteome contains 340 hypothetical proteins, it is important to investigate them to completely understand the mechanisms of its virulence and survival. We have previously reported that the hypothetical protein HP0953 is overexpressed during the first hours of adhesion to inert surfaces, under stress conditions, suggesting its role in the environmental survival of this bacterium and perhaps as a virulence factor.

world journal of gastroenterology

HP0953 hypothetical protein overexpresses and localization as virulence factor from <i>Helicobacter pylori</i> during infection to gastric epithelium cells

HP0953 hypothetical protein overexpresses and localization as virulence factor from Helicobacter pylori during infection to gastric epithelium cells