Open AccessCirculating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma
Author(s) -
Hiroyuki Terasawa,
Hideaki Kinugasa,
Kazuhiro Nouso,
Shumpei Yamamoto,
Maiko Hirai,
Takehiro Tanaka,
Akinobu Takaki,
H. Okada
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i41.7134
Subject(s) - telomerase reverse transcriptase , digital polymerase chain reaction , xenotransplantation , telomerase , liquid biopsy , cancer research , pathology , cancer , medicine , biology , transplantation , gene , polymerase chain reaction , biochemistry
It remains unclear which factors, such as tumor volume and tumor invasion, influence circulating tumor DNA (ctDNA), and the origin of ctDNA in liquid biopsy is always problematic. To use liquid biopsies clinically, it will be very important to address these questions.