Open AccessPreoperative maximal voluntary ventilation, hemoglobin, albumin, lymphocytes and platelets predict postoperative survival in esophageal squamous cell carcinoma
Author(s) -
Shou-Jia Hu,
Xueke Zhao,
Xin Song,
Ling-Ling Lei,
Wen-Li Han,
Ruifeng Xu,
Ran Wang,
Fuyou Zhou,
Liang Wang,
Lidong Wang
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i4.321
Subject(s) - medicine , esophagectomy , proportional hazards model , esophageal cancer , hazard ratio , pulmonary function testing , gastroenterology , survival analysis , cancer , oncology , surgery , confidence interval
Preoperative pulmonary function plays an important role in selecting surgical candidates and assessing postoperative complications. Reduced pulmonary function is associated with poor survival in several cancers, but the prognostic value of preoperative pulmonary function in esophageal squamous cell carcinoma (ESCC) is unclear. Nutritional and systemic inflammation parameters are vital to cancer survival, and the combination of these parameters improves the prognostic value. The hemoglobin, albumin, lymphocytes and platelets (HALP) score is a novel prognostic indicator to reflect the nutritional and inflammation status, but the clinical effects of the HALP score combined with maximal voluntary ventilation (MVV), an important parameter of pulmonary function, have not been well studied in ESCC.