Open AccessEvaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer
Author(s) -
Bilal Rah,
Manzoor Ahmad Banday,
G. M. Bhat,
Omar Javed Shah,
Humira Jeelani,
Fizalah Kawoosa,
Tahira Yousuf,
Dil Afroze
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i36.6093
Subject(s) - epigenetics , pancreatic cancer , medicine , cancer , biology , genetic testing , oncology , bioinformatics , genetics , computational biology , gene
Pancreatic cancer (PC) is one of the deadliest malignancies with an alarming mortality rate. Despite significant advancement in diagnostics and therapeutics, early diagnosis remains elusive causing poor prognosis, marred by mutations and epigenetic modifications in key genes which contribute to disease progression.