Open AccessExosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells
Author(s) -
Haiyan Cui,
Jiansheng Rong,
Ju Chen,
Guo Jie,
Jia-Qin Zhu,
Mei Ruan,
Rongrong Zuo,
Shuang-Shuang Zhang,
Junmei Qi,
Baohua Zhang
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i36.6079
Subject(s) - microrna , cisplatin , cancer research , cancer , cancer cell , microvesicles , medicine , biology , gene , chemotherapy , biochemistry
Gastric cancer is a prevalent malignant cancer with a high incidence and significantly affects the health of modern people globally. Cisplatin (DDP) is one of the most common and effective chemotherapies for patients with gastric cancer, but DDP resistance remains a severe clinical challenge.