Open AccessProteomics identifies a novel role of fibrinogen-like protein 1 in Crohn’s disease
Author(s) -
Xuemei Sun,
Lixin Qiao,
Jing Gong,
Kai Wen,
Zhizhong Xu,
BoLin Yang
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i35.5946
Subject(s) - proteomics , biology , western blot , biomarker , inflammation , pathogenesis , immunology , crohn's disease , gene expression , immune system , proinflammatory cytokine , gene expression profiling , disease , gene , medicine , pathology , genetics
Crohn's disease (CD) is an incurable intestinal disorder with unclear etiology and pathogenesis. Currently, there is a lack of specific biomarkers and drug targets for CD in clinical practice. It is essential to identify the precise pathophysiological mechanism of CD and investigate new therapeutic targets.