Open AccessAdiponectin and the regulation of gastric content volume in the newborn rat
Author(s) -
Huanhuan Wang,
Paul Esemu-Ezewu,
Jingyi Pan,
Julijana Ivanovska,
Estelle B. Gauda,
Jaques Belik
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i33.5566
Subject(s) - adiponectin , medicine , endocrinology , gastric content , gastric emptying , chemistry , stomach , obesity , insulin resistance
Oral intake is dependent on the gastric ability to accommodate the food bolus. Comparatively, neonates have a smaller gastric capacity than adults and this may limit the volume of their milk intake. Yet, we previously reported that the newborn rat gastric milk volume is greatest after birth and, when normalized to body weight, decreases with postnatal age. Such age-dependent changes are not the result of intake differences, but greater gastric accommodation and reduced emptying rate.