Open AccessOncogenic tuftelin 1 as a potential molecular-targeted for inhibiting hepatocellular carcinoma growth
Author(s) -
Mengna Wu,
Wenjie Zheng,
Wenxin Ye,
Li Wang,
Ying Chen,
Jie Yang,
Dengfu Yao,
Min Yao
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i23.3327
Subject(s) - hepatocellular carcinoma , cancer research , small interfering rna , cell growth , biology , immunohistochemistry , flow cytometry , transfection , tissue microarray , pathology , medicine , cell culture , microbiology and biotechnology , immunology , genetics
Abnormal tuftelin 1 (TUFT1) has been reported in multiple cancers and exhibits oncogenic roles in tumor progression. However, limited data are available on the relationship between TUFT1 and hepatocellular carcinoma (HCC), and the exact biological mechanism of TUFT1 is still poorly understood in HCC.