Open AccessLiver injury in COVID-19: Detection, pathogenesis, and treatment
Author(s) -
Yue Cai,
Liping Ye,
Yu Song,
Xin-Li Mao,
Li Wang,
Yanrui Jiang,
Weitao Que,
Shaowei Li
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i22.3022
Subject(s) - covid-19 , liver injury , medicine , coronavirus , outbreak , pathogenesis , disease , betacoronavirus , intensive care medicine , virology , immunology , infectious disease (medical specialty)
In the early December 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 was first reported in Wuhan, China, followed by an outbreak that spread around the world. Numerous studies have shown that liver injury is common in patients with coronavirus disease 2019 (COVID-19), and may aggravate the severity of the disease. However, the exact cause and specific mechanism of COVID-associated liver injury needs to be elucidated further. In this review, we present an analysis of the clinical features, potential mechanisms, and treatment strategies for liver injury associated with COVID-19. We hope that this review would benefit clinicians in devising better strategies for management of such patients.