Open AccessInsight into molecular mechanisms underlying hepatic dysfunction in severe COVID-19 patients using systems biology
Author(s) -
Sarah Hammoudeh,
Arabella Musa Hammoudeh,
Poorna Manasa Bhamidimarri,
Bassam Mahboub,
Rabih Halwani,
Qutayba Hamid,
Mohamed Rahmani,
Rifat Hamoudi
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i21.2850
Subject(s) - transcriptome , fatty liver , biology , cirrhosis , liver disease , fibrosis , alcoholic liver disease , liver function , pathology , gene , disease , medicine , gene expression , genetics , biochemistry
The coronavirus disease 2019 (COVID-19), a pandemic contributing to more than 105 million cases and more than 2.3 million deaths worldwide, was described to be frequently accompanied by extrapulmonary manifestations, including liver dysfunction. Liver dysfunction and elevated liver enzymes were observed in about 53% of COVID-19 patients.