Open AccessS100 calcium binding protein A6 and associated long noncoding ribonucleic acids as biomarkers in the diagnosis and staging of primary biliary cholangitis
Author(s) -
Xi-Hua Dong,
DeZai Dai,
Zhidong Yang,
Xiaoou Yu,
Hua Li,
Hui Kang
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i17.1973
Subject(s) - cholestasis , primary biliary cirrhosis , bile duct , intrahepatic bile ducts , gastroenterology , medicine , biliary tract , messenger rna , primary sclerosing cholangitis , biliary cirrhosis , cirrhosis , bile duct diseases , pathology , biology , gene , disease , autoimmune disease , biochemistry
Primary biliary cholangitis (PBC) is a chronic and slowly progressing cholestatic disease, which causes damage to the small intrahepatic bile duct by immuno-regulation, and may lead to cholestasis, liver fibrosis, cirrhosis and, eventually, liver failure.