Open AccessHigh mortality associated with gram-negative bacterial bloodstream infection in liver transplant recipients undergoing immunosuppression reduction
Author(s) -
Fang Chen,
Xiaoyan Pang,
Chuan Shen,
Longzhi Han,
Yuxiao Deng,
Xiaosong Chen,
Jianjun Zhang,
Qiang Xia,
Yongbing Qian
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i45.7191
Subject(s) - immunosuppression , medicine , gram , liver transplantation , bloodstream infection , immunology , transplantation , biology , bacteria , genetics
Immunosuppression is an important factor in the incidence of infections in transplant recipient. Few studies are available on the management of immunosuppression (IS) treatment in the liver transplant (LT) recipients complicated with infection. The aim of this study is to describe our experience in the management of IS treatment during bacterial bloodstream infection (BSI) in LT recipients and assess the effect of temporary IS withdrawal on 30 d mortality of recipients presenting with severe infection.