Open AccessRole of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis
Author(s) -
Xueling Kang,
L. He,
YaoLi Chen,
Shubin Wang
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i43.6853
Subject(s) - lgr5 , colorectal cancer , cancer stem cell , cancer , carcinogenesis , stem cell marker , oncology , medicine , metastasis , cancer research , biology , immunohistochemistry , pathology , stem cell , genetics
Cancer stem cells (CSCs) are a subpopulation of cancer cells with the potential of self-renewal and differentiation. CSCs play critical roles in tumorigenesis, recurrence, metastasis, radiation tolerance and chemoresistance.