Open AccessDynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in the activity staging of terminal ileum Crohn's disease
Author(s) -
Yin-Chen Wu,
Zhang Xiao,
Xiangtao Lin,
Xianying Zheng,
Dairong Cao,
Zhongshuai Zhang
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i39.6057
Subject(s) - magnetic resonance imaging , crohn's disease , medicine , dynamic contrast , terminal ileum , ileum , diffusion mri , radiology , diffusion weighted magnetic resonance imaging , nuclear magnetic resonance , contrast (vision) , pathology , nuclear medicine , disease , physics , computer science , artificial intelligence
The activity staging of Crohn's disease (CD) in the terminal ileum is critical in developing an accurate clinical treatment plan. The activity of terminal ileum CD is associated with the microcirculation of involved bowel walls. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) can reflect perfusion and permeability of bowel walls by providing microcirculation information. As such, we hypothesize that DCE-MRI and DWI parameters can assess terminal ileum CD, thereby providing an opportunity to stage CD activity.