Open AccessSurveilling Russell body Helicobacter pylori-negative gastritis: A case report and review of literature
Author(s) -
Milena Peruhova,
Monika Peshevska-Sekulovska,
Viktoriya Georgieva,
Gabriela Panayotova,
Dorian Dikov
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i33.5050
Subject(s) - helicobacter pylori , gastritis , medicine , helicobacter infections , gastroenterology , helicobacter , immunology
Russell body gastritis (RBG) is very rare type of chronic inflammation of gastric mucosa. The pathologic hallmark of the disease is Russell bodies (RB) which represent accumulation of eosinophilic cytoplasmic inclusions in endoplasmic reticulum of mature plasma cells (Mott cells). Most published cases are associated with Helicobacter pylori ( H. pylori ) infection because of correlation between plasma cell activation and antigenic stimulation. There are insufficient data about H. pylori -negative RBG and very little is known about the natural course of the disease.