Open AccessImpact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients
Author(s) -
Shiwen Mei,
Zheng Liu,
Fang-Ze Wei,
Jianan Chen,
Zhijie Wang,
Huan Shen,
Juan Li,
Fen Zhao,
Wei Pei,
Zheng Wang,
Xishan Wang,
Qian Liu
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i31.4624
Subject(s) - medicine , colorectal cancer , neoadjuvant therapy , chemoradiotherapy , surgery , oncology , cancer , breast cancer
Epidemiologically, in China, locally advanced rectal cancer is a more common form of rectal cancer. Preoperative neoadjuvant concurrent chemoradiotherapy can effectively reduce the size of locally invasive tumors and improve disease-free survival (DFS) and pathologic response after surgery. At present, this modality has become the standard protocol for the treatment of locally advanced rectal cancer in many centers, but the optimal time for surgery after neoadjuvant therapy is still controversial.