Open AccessLiver structural transformation after partial hepatectomy and repeated partial hepatectomy in rats: A renewed view on liver regeneration
Author(s) -
Keti Tsomaia,
Leila Patarashvili,
Nino Karumidze,
Irakli Bebiashvili,
Elza Azmaipharashvili,
Irina Modebadze,
Diana Dzidziguri,
Merab Sareli,
С. А. Гусев,
Dimitri Kordzaia
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i27.3899
Subject(s) - hepatectomy , liver regeneration , medicine , transformation (genetics) , regeneration (biology) , surgery , chemistry , biology , biochemistry , microbiology and biotechnology , gene , resection
The phenomenon of liver regeneration after partial hepatectomy (PH) is still a subject of considerable interest due to the increasing frequency of half liver transplantation on the one hand, and on the other hand, new surgical approaches which allow removal of massive space-occupying hepatic tumors, which earlier was considered as inoperable. Interestingly, the mechanisms of liver regeneration are extensively studied after PH but less attention is paid to the architectonics of the regenerated organ. Because of this, the question "How does the structure of regenerated liver differ from normal, regular liver?" has not been fully answered yet. Furthermore, almost without any attention is left the liver's structural transformation after repeated hepatectomy (of the re-regenereted liver).