Open AccessClinical relevance of increased serum preneoplastic antigen in hepatitis C-related hepatocellular carcinoma
Author(s) -
Satoyoshi Yamashita,
Akira Kato,
Toshitaka Akatsuka,
Takashi Sawada,
Tomohide Asai,
Noriyuki Koyama,
Kiwamu Okita
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i13.1463
Subject(s) - hepatocellular carcinoma , medicine , clinical significance , antigen , carcinoma , hepatitis , gastroenterology , immunology , pathology
The prognosis of hepatocellular carcinoma (HCC) patients remains poor despite advances in treatment modalities and diagnosis. It is important to identify useful markers for the early detection of HCC in patients. Preneoplastic antigen (PNA), originally reported in a rat carcinogenesis model, is increased in the tissues and serum of HCC patients.