Open AccessCalpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes
Author(s) -
Rujia Xie,
Xiaoxia Hu,
Zheng Lu,
Shuang Cai,
Yu-Si Chen,
Yi Yang,
Ting Yang,
Bing Han,
Qin Yang
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i13.1450
Subject(s) - endoplasmic reticulum , apoptosis , calpain , microbiology and biotechnology , unfolded protein response , biology , chemistry , biochemistry , enzyme
Calpain-2 is a Ca 2+ -dependent cysteine protease, and high calpain-2 activity can enhance apoptosis mediated by multiple triggers.