Open AccessTumor-infiltrating platelets predict postoperative recurrence and survival in resectable pancreatic neuroendocrine tumor
Author(s) -
Shuai Xu,
Hua Xu,
Wen Quan Wang,
Shuo Li,
Hao Li,
Tian Jiao Li,
Wu Hu Zhang,
Liang Liu
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i41.6248
Subject(s) - medicine , platelet , pancreatic neuroendocrine tumor , univariate analysis , multivariate analysis , biomarker , metastasis , oncology , neuroendocrine tumors , immunohistochemistry , mean platelet volume , gastroenterology , pathology , cancer , biochemistry , chemistry
Platelets have been reported to participate in tumor cell growth, extravasation, epithelial-mesenchymal transition, metastasis, and drug resistance. However, the importance of platelets in pancreatic neuroendocrine tumor (pNET) lacks adequate literature support. The predictive value of tumor-infiltrating platelets (TIPs) in pNET remains unclear.