Open AccessTherapeutic potential of menstrual blood stem cells in treating acute liver failure
Author(s) -
Panpan Cen,
Linxiao Fan,
Jie Wang,
Jiajia Chen,
Lanjuan Li
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i41.6190
Subject(s) - stem cell , mesenchymal stem cell , transplantation , medicine , liver function , spleen , alanine transaminase , in vivo , pathology , biology , genetics , microbiology and biotechnology
Acute liver failure (ALF) is a significant and complex hepatic insult that may rapidly progress to life-threatening conditions. Recently, menstrual blood stem cells (MenSCs) have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition, low immunogenicity, a greater capacity of self-renewal and multi-lineage differentiation, making them promising candidates for stem cell-based therapy to revolutionize the treatment strategies for liver failure.