Open AccessGender differences in vascular reactivity of mesenteric arterioles in portal hypertensive and non-portal hypertensive rats
Author(s) -
Bin Zhang,
Linhua Ji,
Chenggang Zhang,
Gang Zhao,
Zijian Wu
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i39.5953
Subject(s) - medicine , endocrinology , portal hypertension , splanchnic , hyperdynamic circulation , circulatory system , mesenteric arteries , vascular resistance , portal venous pressure , norepinephrine , blood pressure , artery , hemodynamics , cirrhosis , dopamine
Portal hypertension (PHT) is primarily caused by an increase in resistance to portal outflow and secondarily by an increase in splanchnic blood flow. Vascular hyporeactivity both in systemic circulation and in the mesenteric artery plays a role in the hyperdynamic circulatory syndrome.