Open AccessHepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol andAPOEε4allele
Author(s) -
Karina González-Aldaco,
Sonia Román,
Rafael Torres-Valadez,
Claudia OjedaGranados,
Luis A. Torres-Reyes,
Arturo Panduro
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i38.5826
Subject(s) - medicine , hepatitis c virus , cholesterol , apolipoprotein e , hepatitis c , gastroenterology , population , allele , immunology , biology , virus , gene , genetics , disease , environmental health
Cholesterol is related to improvements in the rate of sustained virological response and a robust immune response against the hepatitis C virus (HCV). APOE gene polymorphisms regulate cholesterol levels modifying the course of the HCV infection. The relationship between cholesterol, APOE alleles, and the outcome of HCV infection has not been evaluated in the admixed population of Mexico.