Open AccessLncRNA-ATB promotes autophagy by activating Yes-associated protein and inducing autophagy-related protein 5 expression in hepatocellular carcinoma
Author(s) -
Chuanzhuo Wang,
Guangxin Yan,
Diansheng Dong,
Xin He,
Zhaoyu Liu
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i35.5310
Subject(s) - autophagy , hepatocellular carcinoma , protein expression , cancer research , downregulation and upregulation , biology , gene , apoptosis , biochemistry
Long non-coding RNAs (lncRNAs) play important roles in many diseases, including hepatocellular carcinoma (HCC). Autophagy is a metabolic pathway that facilitates cancer cell survival in response to stress. The relationship between autophagy and the lncRNA-activated by transforming growth factor beta (lncRNA-ATB) in HCC remains unknown.