Open AccessSmall bowel capsule endoscopy and treat-to-target in Crohn's disease: A systematic review
Author(s) -
Catherine Le Berre,
Caroline Trang-Poisson,
Arnaud Bourreille
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i31.4534
Subject(s) - capsule endoscopy , medicine , context (archaeology) , endoscopy , crohn's disease , disease , cochrane library , gastroenterology , medline , randomized controlled trial , paleontology , political science , law , biology
Crohn's disease (CD) can affect the entire gastrointestinal tract. Proximal small bowel (SB) lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries. The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prognosis with potential therapeutic implications. Because of the weak correlation that exists between symptoms and endoscopic disease activity, the "treat-to-target" paradigm has been developed, and the associated treatment goal is to achieve and maintain deep remission, encompassing both clinical and endoscopic remission. Small bowel capsule endoscopy (SBCE) allows to visualize the mucosal surface of the entire SB. At that time, there is no recommendation regarding the use of SBCE during follow-up.