Open Access
Nuclear magnetic resonance-based metabolomics and metabolic pathway networks from patient-matched esophageal carcinoma, adjacent noncancerous tissues and urine
Author(s) -
Jiahao Liang,
Yan Lin,
Ting Ouyang,
Wan Tang,
Yao Huang,
Wei Ye,
Zhao Jin,
Zhening Wang,
Changchun Ma
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i25.3218
Subject(s) - glutaminolysis , metabolomics , metabolome , metabolite , urinary system , metabolic pathway , glutamine , citric acid cycle , urine , glycolysis , taurine , biology , biomarker , metabolism , chemistry , cancer research , pathology , biochemistry , endocrinology , medicine , bioinformatics , amino acid
Several studies have demonstrated a correlation between esophageal cancer (EC) and perturbed urinary metabolomic profiles, but none has described the correlation between urine metabolite profiles and those of the tumor and adjacent esophageal mucosa in the same patient.