Open AccessClinical characteristics of non-alcoholic fatty liver disease in Chinese adult hypopituitary patients
Author(s) -
Xianxian Yuan,
Huijuan Zhu,
Hui Pan,
Shi Chen,
Zeyu Liu,
Yue Li,
Linjie Wang,
Lin Lü,
Hongbo Yang,
Fengying Gong
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i14.1741
Subject(s) - medicine , hypopituitarism , dyslipidemia , fatty liver , cirrhosis , population , retrospective cohort study , gastroenterology , diabetes insipidus , liver disease , endocrinology , obesity , disease , environmental health
Patients with hypothalamic-pituitary disease have the feature of central obesity, insulin resistance, and dyslipidemia, and there is increased prevalence of liver dysfunction consistent with non-alcoholic fatty liver disease (NAFLD) in this population. The causes of hypopituitarism in the reported studies varied and combined pituitary hormone deficiency including central diabetes insipidus is much common in this population. This retrospective cross-sectional study was performed to analyze the clinical characteristics and related factors with NAFLD and cirrhosis in Chinese adult hypopituitary/panhypopituitary patients.