Open AccessAccuracy of multi-echo Dixon sequence in quantification of hepatic steatosis in Chinese children and adolescents
Author(s) -
Yuzhen Zhao,
Yong Gan,
Jian Zhou,
Jiaqi Liu,
Wenxi Cao,
Sihang Cheng,
Da-Ming Bai,
Mengzhu Wang,
Fang-Qin Gao,
Shiwei Zhou
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i12.1513
Subject(s) - steatosis , medicine , overweight , nonalcoholic fatty liver disease , magnetic resonance imaging , fatty liver , liver biopsy , gastroenterology , obesity , radiology , biopsy , disease
Nonalcoholic fatty liver disease (NAFLD) is currently the outstanding cause of chronic liver disease in children and adolescents, especially in overweight and obese groups. Liver biopsy is the reference standard to diagnose NAFLD but invasive, thus it is not the best choice in clinical diagnosis and follow-up. Magnetic resonance (MR) is widely used in clinical trials to noninvasively quantify liver fat content in adults and children in foreign countries. While currently, it is rarely used in Chinese children and adolescents. We postulated that quantifying hepatic steatosis by MR could be extended to children and adolescents in China.