Open AccessTotal polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway
Author(s) -
Yue Lu,
Li Leng,
Jinwei Zhang,
Xiaoqin Zhong,
Jianan Wei
Publication year - 2018
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v24.i26.2867
Subject(s) - occludin , paracellular transport , myosin light chain kinase , tight junction , barrier function , caco 2 , tumor necrosis factor alpha , microbiology and biotechnology , chemistry , blot , downregulation and upregulation , biology , myosin , cell , biochemistry , endocrinology , permeability (electromagnetism) , membrane , gene
To explore the protective effects and underlying mechanisms of total polysaccharides of the Sijunzi decoction (TPSJ) on the epithelial barriers in vitro .