Open AccessDendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancerin vitro
Author(s) -
Chen Jiang,
Xiaozhong Guo,
Hongyu Li,
Jiajun Zhao,
Wei Xu
Publication year - 2017
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v23.i5.817
Subject(s) - cytotoxic t cell , microbiology and biotechnology , monoclonal antibody , immune system , antigen , chemistry , dendritic cell , viability assay , mtt assay , antibody , biology , cancer research , in vitro , immunology , biochemistry
To investigate the enhanced cytotoxic T lymphocyte responses against pancreatic cancer (PC) in vitro induced by dendritic cells (DCs) engineered to secrete anti-DcR3 monoclonal antibody (mAb).